Please use this identifier to cite or link to this item: https://hdl.handle.net/10316.2/31751
Title: Forensic y-str study in y-chromosome abnormalities
Authors: Silva, J.
Ribeiro, T.
Gonçalves, J.
Geada, H.
Keywords: AZF regions;Y-ST Rs;Microdeletions
Issue Date: 2010
Publisher: Imprensa da Universidade de Coimbra
International Academy of Legal Medicine
Journal: http://hdl.handle.net/10316.2/2632
Abstract: Y-chromosome infertility is usually caused by deletions of genetic material in Azoospermia Factor (AZF) regions, localized in three nonoverlapping Yq regions – AZFa, AZFb and AZFc. However, some of the Y-ST Rs routinely studied in Forensic Genetics with multiplex kits are localized in these three regions giving rise to microdeletions observed in some loci. Rare alleles were also encountered in these samples with Y-chromosome structural changes. A complete Y-ST R profile in a sample from a female individual was detected which may raise ethical implications. The aim of this work is to assess the validity in the use of Y-ST R multiplex systems in structurally abnormal Y-chromosomes, which may occur in forensic casework analysis
URI: https://hdl.handle.net/10316.2/31751
ISBN: 978-989-26-0173-1 (PDF)
DOI: 10.14195/978-989-26-0173-1_15
Rights: open access
Appears in Collections:Acta medicinae legalis et socialis

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