Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316.2/31767
Title: | 20 SNP-Plex as a complement method in paternity testing | Authors: | Dario, P. Ribeiro, R. Geada, H. |
Keywords: | SNPs;Paternity testing;SNaPshot | Issue Date: | 2010 | Publisher: | Imprensa da Universidade de Coimbra International Academy of Legal Medicine |
Journal: | http://hdl.handle.net/10316.2/2632 | Abstract: | This study intended to examine a set of 20 autosomal Single Nucleotide Polymorphisms (SN Ps) selected from the 52-plex developed by the SN PforID Consortium for human identification and to study its usefulness in investigation of paternity cases. We designed two 10-plexes and investigated 50 paternity cases, previously examined in this laboratory with standard ST R methodologies. There was a total agreement between exclusion and not exclusion cases with the results obtained by ST R analysis, except for one case where it was not possible to exclude the father with SN P analysis, probably due to the small number of SN Ps studied. In paternity exclusions, between one and seven incompatibilities were detected for the SN P loci studied. This study demonstrates that analysis of a small number of SN P loci, as 20 polymorphisms, can be very useful in biological kinship investigation as a complement to standard ST R methodologies, being an advantage to increase the number of loci to strengthen SN P study as a complement methodology | URI: | https://hdl.handle.net/10316.2/31767 | ISBN: | 978-989-26-0173-1 (PDF) | DOI: | 10.14195/978-989-26-0173-1_22 | Rights: | open access |
Appears in Collections: | Acta medicinae legalis et socialis |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
21-_acta_medicinae_legalis.pdf | 1.42 MB | Adobe PDF |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.